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BIC Prof. Alexey Kostikov offers course on PET radiochemistry in the fall of 2015

The course deals with in vivo ‪imaging‬ using radioactive isotopes and is primarily focused on positron emission tomography (‪PET‬). PET has found research and clinical application in oncology, neurology and cardiology and is an especially powerful modality for imaging of neuroreceptors, cerebral blood flow and abnormal protein deposits in the brain. The course covers most of the topics related to PET from isotope production and radiotracers syntheses to image acquisition and reconstruction. Examples of PET studies of various neurotransmission systems and misfolded ‪‎protein‬ accumulation as well as their implications in various ‪#‎neurodegenerative‬ diseases and ‪‎psychiatric‬ conditions will be explained. Understanding how ‪‎radiochemistry‬, physics and math intermingle with the molecular biology and medicine will result in a deeper insight into the PET radiotracer design and the methods necessary to properly acquire and interpret the data.