脡velyne Vinet
Associate聽Professor, Department of Medicine, Division of Rheumatology, Division of Clinical Epidemiology
Dr. Vinet鈥檚 research focuses on reproductive issues in women with rheumatic diseases, with the goal of improving reproductive outcomes in women with rheumatic disease and their offspring.
She has created the world鈥檚 largest cohort of systemic lupus erythematosus (SLE) offspring, leading to novel findings on the increased risk of autism spectrum disorders, congenital heart defects, and stillbirths in SLE offspring. Using a large US database, Dr. Vinet also assessed the risk of serious infections in children of patients with rheumatoid arthritis exposed to TNF inhibitors. Currently, Dr. Vinet is establishing an international cohort of SLE pregnancies and conducting a randomized controlled trial to improve preeclampsia knowledge and aspirin adherence in pregnant SLE women.
Clinical research is focused on reproductive issues in women with rheumatic diseases, with the goal of improving reproductive outcomes in women with rheumatic disease and their offspring. Specifically, research is on adverse pregnancy outcomes, pregnancy risks, and other outcomes in women with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) using various administrative database sources. Current projects include 1) establishing an international cohort of SLE pregnancies to monitor adverse pregnancy outcomes, 2) evaluating the patterns of aspirin use in pregnant women with SLE in Canada, receiving standard of care (i.e. unexposed to a specifically designed patient educational tool) by conducting a randomized controlled, and 3) assessing the needs, barriers, and facilitators to pregnancy for women with RA and SLE with focus groups.
- Assessing the risk of serious infections in children born to women with chronic inflammatory arthritis using biologic disease-modifying anti-rheumatic drugs using the large administrative database IBM MarketScan.
- International prospective cohort of unselected SLE pregnancies to determine predictors of adverse pregnancy outcomes
- Evaluating the patterns of aspirin use in pregnant women with SLE in Canada, receiving standard of care (i.e. unexposed to a specifically designed patient educational tool) by conducting a randomized controlled