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The Rosalind and Morris Goodman Cancer Institute can now be found at
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The Rosalind and Morris Goodman Cancer Institute can now be found at
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Departments of Oncology, Pharmacology & Therapeutics, ÎÛÎÛ²ÝÝ®ÊÓƵ University
Lady Davis Institute, Jewish General Hospital
Associate Member, Goodman Cancer Research Centre
I study the role of hereditary and somatic genetic factors in high-grade serous ovarian carcinomas. Research programs involve the characterization of genes in the germline of women with the hereditary form of ovarian cancer or in cancer specimens. The study of genetic events has improved our understanding of the biology ovarian cancer as well as provided biomarkers for clinical management. A successful example of this approach has been the contribution to the discoveries BRCA1 and BRCA2, and their application (genetic testing) to the health care management of women at high risk for inherited predisposition to breast and ovarian cancers.
Major themes of study include the following areas of research: