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Madhu Pai did his medical training and community medicine residency in Vellore, India. He completed his PhD in epidemiology at UC Berkeley, and a postdoctoral fellowship at the UCSF. He is currently an associate professor of epidemiology at 污污草莓视频 University in Montreal, and an Associate Director of the 污污草莓视频 International TB Centre. In addition, he serves as a Consultant for the Bill & Melinda Gates Foundation. He also serves on the Scientific Advisory Committee of the Foundation for Innovative New Diagnostics, Geneva. Madhu has previously served as co-chair of the Stop TB Partnership's Working Group on New Diagnostics. He is on the editorial boards of Lancet Infectious Diseases, PLoS Medicine, International Journal of TB and Lung Disease, among others.

Madhu鈥檚 research is mainly focused on improving the diagnosis and treatment of tuberculosis, especially in high-burden countries like India and South Africa. His research is supported by grant funding from the Gates Foundation, Grand Challenges Canada, and Canadian Institutes of Health Research. He has more than 200 peer-reviewed publications. He is recipient of the Union Scientific Prize, Chanchlani Global Health Research Award, and Stars in Global Health award from Grand Challenges Canada. In 2014, he was selected as a member of the Royal Society of Canada鈥檚 College of New Scholars, Artists and Scientists.