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Manuel Friese will present, "Disentangling neurodegeneration in multiple sclerosis".Ìý

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Speaker: Manuel Friese, MD, PhD

University Medical Center Hamburg-Eppendorf, Institute of Neuroimmunology and Multiple Sclerosis, Hamburg, GermanyÌý

´¡²ú²õ³Ù°ù²¹³¦³Ù:ÌýMultiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) with continuous neuronal loss. Treatment of clinical progression remains challenging due to lack of insights into pathways that determine neuronal vulnerability to inflammation. Although inflammatory relapses can be effectively suppressed by immunomodulatory therapies, patients suffer from ongoing neurodegeneration with highly variable disease progression. Here I will explore the pathomechanisms of inflammation-induced neurodegeneration and how to translate these findings into potential drug treatments.

µþ¾±´Ç:ÌýManuel A. Friese studied medicine at the Universities of Hamburg, Oxford and University College London and received his MD in 2001. He completed his neurology training at the Universities of Tübingen and Hamburg. After his postdoctoral training at the University of Oxford from 2004––2008, he started his laboratory as an Emmy Noether research fellow of the Deutsche Forschungsgemeinschaft at the University of Hamburg. Since 2013 he has been consultant neurologist and Professor of Neuroimmunology at the University of Hamburg and since 2014 director of the INIMS. His laboratory focuses on inflammatory and neurodegenerative aspects of neuroimmunological and neuroinfectious diseases.

Supported by the generosity of the Killam Trusts , The Neuro’s Killam Seminar series hosts outstanding guest speakers whose research is of interest to the scientific community at The Neuro and ÎÛÎÛ²ÝÝ®ÊÓƵ University.