ÎÛÎÛ²ÝÝ®ÊÓƵ

Nahum Sonenberg

Academic title(s): 

Distinguished James ÎÛÎÛ²ÝÝ®ÊÓƵ Professor

Gilman Cheney Chair, Rosalind and Morris Goodman Cancer Institute

Nahum Sonenberg
Branch: 
Université ÎÛÎÛ²ÝÝ®ÊÓƵ
Department: 
Biochimie
Areas of expertise: 
  • Translational control
  • eIF4E
  • cancer
  • memory
  • autism
  • Fragile-X syndrome
Biography: 

Dr. Sonenberg is a Distinguished James ÎÛÎÛ²ÝÝ®ÊÓƵ Professor and Gilman Cheney Chair in the Department of Biochemistry and the Rosalind and Morris Goodman Cancer Institute (formerly Research Centre) at ÎÛÎÛ²ÝÝ®ÊÓƵ University.

Dr. Sonenberg studies the molecular basis of the control of protein synthesis in eukaryotic cells and its importance in diseases such as cancer, obesity, diabetes and neurological diseases. His research focuses primarily on the elucidation of the mechanism of translation initiation in eukaryotes and its regulation during development, differentiation and neoplasia. Dr. Sonenberg carried out pioneering and fundamental work that laid the basis for the understanding of how translation initiation factors promote ribosome binding, and the regulation of initiation factor activity by extracellular stimuli (growth factors, hormones, G-protein-coupled receptor agonists, cytokines and mitogens), and viruses. He made seminal discoveries demonstrating that control of translation initiation is implicated in cancer, learning and memory, autism and fragile-X syndrome.

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