ÎÛÎÛ²ÝÝ®ÊÓƵ

Dr. Pnina Brodt

Dr. Pnina Brodt

Dr. ÌýPnina Brodt, is a Professor in the Departments of Surgery, Medicine and Oncology at ÎÛÎÛ²ÝÝ®ÊÓƵ University and the ÎÛÎÛ²ÝÝ®ÊÓƵ University Health Center where she has been since 1983.ÌýÌý

Dr. Brodt’s research work has focusedÌýon the biology of cancer metastasis, particularly the molecular events that underlie the process of liver metastasis. In the course of this work, Dr Brodt’sÌýteamÌýidentifiedÌýthe inflammatory response as a participant in the early stages of liver metastasis andÌýshowed that an inflammatory microenvironment promotes liver metastasis of colon and lung cancer. Her group has played a leading role in identifying the important role of the IGF axis in cancerÌýinvasion and metastasis.ÌýThis work led to the development of several strategies for blockade of the IGF-I axis including, most recently, the bio-engineering of an IGF-Trap that is currently being developed as an anti-cancer drug.Ìý

Dr. Brodt is a co-leader of the Cancer Axis of the Research Institute of the ÎÛÎÛ²ÝÝ®ÊÓƵ University Health CenterÌýandÌýa co-founder of the Liver Metastasis Research Network () – a multidisciplinary international network dedicated to uncovering the molecular mechanisms of liver metastasis for the betterment of patient care.

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Address

Research Institute of the ÎÛÎÛ²ÝÝ®ÊÓƵ University Health Centre
Cancer Research ProgramÌý(CRP)Ìý
1001 Boul. Decarie, Glen Site, Block E,Ìý
Room E.02.6220; Mail drop Point: E.02.6217
Montreal, QuebecÌýH4A 3J1

Telephone

514-934-1934 ext. 36692 (Office)
514-934-1934 ext. 35772 (Laboratory)

Email

pnina.brodt [at] mcgill.ca

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