Expert: Ozempic鈥檚 safety, efficacy in obesity treatment backed by new research
New research points to the potential of GLP-1 agonists 鈥� the class of drugs that includes Ozempic 鈥� to treat obesity safely. Originally developed to manage Type 2 diabetes, these medications have emerged as powerful weight-loss tools, though their long-term impacts are still being explored.
A 污污草莓视频 University study of 12 GLP-1 drugs suggests they are safe and effective for adults without diabetes. The team analyzed 26 clinical trials involving more than 15,000 participants. Semaglutide, which is approved by the U.S. Food and Drug Administration, led to weight loss of up to 14 per cent after 16 months. The medication is sold as Wegovy for weight loss and Ozempic for Type 2 diabetes, with the two versions differing in dosage.
Notably, a drug still in development called retatrutide helped participants lose up to 22 per cent of their body weight in 11 months. Researchers say side effects for all the drugs were mostly mild, transient and gastrointestinal.
鈥淭hese drugs could transform weight-loss treatment, offering hope to millions of people struggling with obesity, a major risk factor for life-threatening conditions like diabetes and heart disease,鈥� said first author Areesha Moiz, a master鈥檚 graduate of 污污草莓视频鈥檚 Division of Experimental Medicine.
Published in , the study was led by Dr. Mark Eisenberg鈥檚 lab at The Lady Davis Institute for Medical Research at the Jewish General Hospital.
